diff --git a/README.md b/README.md index 9c0c3cb0205f91f11a5ed816af6c314a953c984f..1b6162a2e42a0055f2b8531314d2e3f4d6b5a125 100644 --- a/README.md +++ b/README.md @@ -46,14 +46,25 @@ performance difference between pleated hydrophobic filters and electrostatic fil - ASTM standards uses latex spheres. could potentially use gold particles - charge neutralizer recommended - but Lorena said viruses are typically polarized so maybe charge neutralization could be ignored initially +- optical particle counter [^opc]- fancy once can be used to measure particle size with lorentz mie scattering, but it shouldn't take too much work to make our own that just counts. + - visible laser : wavelength and power determine particle size resolution, higher power --> smaller particles, limited to >100nnm (intracavity systems for smaller than that) + - photodetector placed where particles scatter light : placement could be difficult if the particles have a large area to explore, but photomulitplier tube could fix + - isokinetic sampling probes[^isokineticProbes] pull representative particle samples into the OPCs - so you don't care about area for PMT and can put the OPCs in a light box instead of the entire appartus -## shopping list -- nebulizer for aerosolization [^nebulizer_selection] +## proposed testing device +measure filtration efficiency and pressure difference with non-biological colloidal particles: + + +could also get away with only one OPC by adding a bypass around the test filter and a switch + + +## equipment needed +- nebulizer for aerosolization [^nebulizer] - three-jet Collison nebulizer? -- impinger for collection - wet and dry thermometer / hygrometer for humidity +- OPC : photodiodes or PMTs - andersen sampler?? could be nice to bin different size particles - six-stage viable particle cascade impactor - +- OPC would be better than andersen sampler ### Resources [^DIYmask]: University of Cambridge [DIY mask efficacy testing](https://www.researchgate.net/publication/258525804_Testing_the_Efficacy_of_Homemade_Masks_Would_They_Protect_in_an_Influenza_Pandemic) @@ -64,4 +75,6 @@ performance difference between pleated hydrophobic filters and electrostatic fil [^aerodynamics]: [Aerodynamic Characteristics of RNA concetration of SARS-CoV-2](https://www.biorxiv.org/content/10.1101/2020.03.08.982637v1.abstract) [^VFEreport]: [Nelson Laboratories: Viral Filtration Efficiency (VFE) at increased challenge level](https://gitlab.cba.mit.edu/pub/coronavirus/tracking/uploads/164d119b5a7a5751c685a6677378668a/ER_2235600_Attachment_5_Viral_Filtration_Efficiency.pdf) [^nelson]: [Nelson lab filtration test](https://www.nelsonlabs.com/testing/bacterial-viral-filtration-efficiency-bfe-vfe/?industry=medical-devices&category=protective-barriers-material-performance) -[^nebulizer_selection]: [Nebulizer selection from CH tech](http://chtechusa.com/Manuals/Selecting%20the%20Model%20and%20Configuration%20Instructions.pdf) +[^nebulizer]: [Nebulizer selection from CH tech](http://chtechusa.com/Manuals/Selecting%20the%20Model%20and%20Configuration%20Instructions.pdf) +[^opc]: [optical particle counter](http://www.cas.manchester.ac.uk/restools/instruments/aerosol/opc/) +[^isokineticProbes]: [Isokinetic particle Sampling](http://www.climet.com/accessories/isoprobes.html) \ No newline at end of file